Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins

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Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins

Germ plasm, a specialized cytoplasm present at the posterior of the early Drosophila embryo, is necessary and sufficient for germ cell formation. Germ plasm is rich in mitochondria and contains electron dense structures called polar granules. To identify novel polar granule components we isolated proteins that associate in early embryos with Vasa (VAS) and Tudor (TUD), two known polar granule a...

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ژورنال

عنوان ژورنال: Mechanisms of Development

سال: 2008

ISSN: 0925-4773

DOI: 10.1016/j.mod.2008.06.005